Changes in nasal flora after using povidone-iodine in nasal septoplasty surgery
Caner Şahin1, Kamran Sarı2, Neziha Yılmaz3, Gulsum Genis4
1Sakarya Akyazı Devlet Kulak Burun Boğaz Kliniği, Hastanesi, Sakarya, Türkiye
2Yozgat Üniversitesi Tıp Fakültesi Kulak Burun Boğaz Anabilim Dalı, Yozgat, Türkiye
3Yozgat Üniversitesi Tıp Fakültesi Mikrobiyoloji Anabilim Dalı, Yozgat, Türkiye
4Sakarya Akyazı Devlet Enfeksiyon Hastalıkları Kliniği, Hastanesi, Sakarya, Türkiye
Keywords: Antiseptics, culture, nasal surgical procedures.
Abstract
OBJECTIVE: This study aims to investigate the effect of povidone-iodine antisepsis on nasal flora prior to septoplasty surgery.
METHODS: The study included a total of 44 patients (23 males, 21 females; mean age 36 years; range 18 to 71 years) with a diagnosis of nasal septal deviation who had undergone surgery. Preoperative nasal swab materials were taken by sterile cotton swabs from the region of the nasal cavity and skin of the nasal tip. Cultures from the same areas were taken 10 minutes after the application of 10% povidone-iodine.
RESULTS: Five methicillin-sensitive Staphylococcus aureus (S. aureus), four Staphylococcus epidermidis (S. epidermidis), two methicillin-resistant S. aureus, and one diphtheroid species were revealed in nasal mucosa cultures before/after application of povidone-iodine. Six S. epidermidis, five methicillin-sensitive S. aureus, and one methicillin-resistant S. aureus were revealed in nasal tip skin before/after application of povidone-iodine.
CONCLUSION: In our study, we demonstrated that microbiological changes were harmonious, as noted in the literature. Application of antiseptic povidone-iodine did not decrease the microbiological population. Two patients (4%) had chemical conjunctivitis after surgery. Due to potential allergic and chemical side effects, we suggest to discuss the use of antiseptic solutions prior to closed technique septoplasty.