Transoral robotik cerrahi uygulanan baş boyun yassı hücreli kanser hastalarında human papilloma virüs insidansı
Ahmet Altıntaş1, Arzu Karaman Koç2, Kamil Hakan Kaya2, Yakup Yegin2, Mustafa Çelik2, Fatma Tülin Kayhan2
1İskilip Atıf Hoca Devlet Hastanesi, Kulak Burun Boğaz Kliniği, Çorum, Türkiye
2Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Kulak Burun Boğaz Hastalıkları Kliniği, İstanbul, Türkiye
Keywords: Human papillomavirus, squamous cell carcinoma, transoral robotic surgery.
Abstract
OBJECTIVE: This study aims to assess the incidence of human papillomavirus (HPV) in patients with squamous cell carcinoma (SCC) of the head and neck treated by transoral robotic surgery (TORS).
METHODS: Between December 2009 and March 2013, a total of 30 patients with larynx (n=24), oral cavity and oropharyngeal SCC (n=6) (28 males, 2 females; mean age 66.4±13.5 years; range 41 to 77 years) who had been treated by TORS at our clinic were included in this study. The paraffin blocks of the pathological specimens taken from the patients were immunohistochemically stained with appropriate paint for specific HPV serotypes and were examined by light microscopy. The staining results were regarded as positive and negative.
RESULTS: No staining was detected in any of the patients included in this study to make us think of the presence of HPV.
CONCLUSION: Future studies with larger number of patients should be done to explore the presence and the role of HPV in the etiology of the SCC of the head and neck.