Praxis of Otorhinolaryngology

Yetkin Zeki Yilmaz1, Doğan Çakan1, Begüm Bahar Yilmaz2, Musa Musayev1, Atakan Demir1, Aysegul Batioglu-karaaltin1

1Istanbul Üniversitesi-cerrahpaşa, Cerrahpaşa Tıp Fakültesi Kulak Burun Boğaz Anabilim Dalı, Istanbul, Türkiye
2Istanbul Başakşehir Çam ve Sakura Şehir Hastanesi, Kulak Burun Boğaz Kliniği, Istanbul, Türkiye

Keywords: COVID-19, diagnosis, larnygectomy, larynx cancer, symptoms.

Abstract

OBJECTIVE: The aim of this study was to investigate the frequency and clinical severity of coronavirus disease 2019 (COVID-19) disease in patients with total laryngectomy.

METHODS: This retrospective study was conducted with 114 participants (102 males, 12 females; mean age: 65.9±10.4 years; range, 40 to 92 years). Fifty-seven patients who underwent total laryngectomy in our clinic between June 2014 and June 2018 were included in the study group. Among the healthy individuals who applied to our clinic, 57 people were included in the control group. The frequency of COVID-19 was determined in the study groups. The severity of COVID-19 symptoms of the patients was questioned, and the obtained data were analyzed.

RESULTS: The study group consisted of 52 (91.2%) male and five (8.8%) female patients, and the control group consisted of 50 (87.7%) male and seven (12.3%) female participants. The mean ages of the groups were 65.9±10.4 years (median age: 65 years; range, 40 to 92 years) for study group and 65.7±11.0 years (median age: 65 years; range, 40 to 94 years) for control group. The frequency of COVID-19 in study group was significantly lower compared to control group (p=0.001). In the evaluation of COVID-19 symptoms, cough and smell disorder symptoms were found to be significantly more severe in study group (p=0.001, p=0.001, respectively). The number of inpatients treated in study group was significantly higher than in control group (p=0.015).

CONCLUSION: The incidence of COVID-19 may be lower in patients with total laryngectomy compared to the normal population. However, the clinical course of COVID-19 may be more severe in patients with total laryngectomy compared to the normal population.